five.17 Bone-Marrow Despair Promethazine HCl and codeine phosphate oral Resolution ought to be used with caution in clients with bone-marrow despair. Leukopenia and agranulocytosis have already been reported, ordinarily when promethazine continues to be Utilized in Affiliation with other acknowledged marrow-harmful brokers.From Mayo Clinic towards

Just take this medication by mouth with or without foodstuff as directed by your doctor, typically just about every four to 6 several hours as essential. This medication may be taken with food stuff if belly upset takes place. Consume lots of fluids any time you use this medication unless otherwise directed by your medical professional.From Mayo Cl